An international trial has investigated the potential immune-boosting effects of the tuberculosis BCG vaccine against COVID-19. The results show that the risk of developing the disease during the first six months after vaccination was not reduced in participants as originally hoped for. Nearly 4,000 healthcare workers took part in the BRACE trial across 36 sites from five countries, including the Germans Trias Hospital. Researchers from an IGTP tuberculosis research group were involved in the development of the study, which has been published in the New England Journal of Medicine.
At the IGTP TODAY
A state-of-the-art super-resolution fluorescence confocal microscope, called Abberior Infinity, was installed in the high-level biosafety (NCB3) facility of the Centre for Comparative Medicine and Bioimage (CMCiB). The equipment of this class, unique in the region, is a powerful tool for anyone aiming to perform advanced microscopy studies on fully infectious Level 3 pathogens (HIV, SARS-CoV-2, Monkey Pox, TB etc.) The microscope is available for use by all internal and external users via IGTP Microscopy Platform.
A preclinical study with support from the Spanish Association Against Cancer has identified a potential treatment approach for patients with hepatoblastoma, which involves combining standard chemotherapy with a drug currently undergoing clinical trials. The research was conducted using patient samples and animal and laboratory models, and has been led by Dr Josep M. Llovet, professor at the UB and group leader at IDIBAPS, and Dr Carolina Armengol, group leader at IGTP and member of CIBEREHD.
Hyposfix, a new medical device to improve paediatric urological surgeries, has been developed by researchers at Germans Trias Hospital, with support from IGTP
The expertise and innovation spirit of researchers at Germans Trias Hospital's Paediatric Surgery Service has resulted in a new medical device for the treatment of hypospadias: Hyposfix, a urological separator-fixator. This device, which will be launched to market soon, is the result of an idea and a project led at Germans Trias i Pujol Research Institute (IGTP).
CMCiB participates in the preclinical studies of Rob Surgical's surgical robot, the first one designed and manufactured in Catalonia
The centre reaches a milestone in its track-record by adding the first Good Laboratory Practice study in its portfolio where the tested product at the centre will reach clinical trials in humans in accordance with international Good Clinical Practice.
Researchers from the Innate Immunity group at the Germans Trias i Pujol Research Institute (IGTP) have developed a new immunotherapy based on a monoclonal antibody directed against tumour macrophages. The results obtained lay the foundations for a new treatment for patients with lung cancer, with the potential to be applied to other solid tumours. The study has been published in the journal eBioMedicine.
The new episode of the podcast 'Un bri de ciència' is presented under the title "La diabetis tipus 1: quan la defensa t'ataca" (Type 1 diabetes: when your defences attack you). Researcher Marta Vives Pi explains the problems of autoimmune diseases, with an emphasis on type 1 diabetes.
EATRIS, the European infrastructure for translational medicine, has appointed 7 Expert Centres, to provide high value added services historically offered by EATRIS Coordination and Support. Those expert services that are complementary to the existing laboratory research services offered by EATRIS institutions cover crucial areas such as innovation management, regulatory strategy, translational feasibility, and early health technology assessment. With 7 newly appointed Expert Centres, EATRIS will continue serving Europe's translational research efforts and growing demand for expert services.
The European Commission has announced the results of the second WomenTechEU call, which aims to support innovative European deep-tech companies founded by women. This year, 134 women-led companies have been chosen to receive a €75,000 grant to assist with their innovation process and company growth. Among the selected companies are four spin-offs from the Germans Trias i Pujol Research Institute (IGTP). These companies represent a portion of the 20 Catalan women-led companies selected in the WomenTechEU call.
Researchers of the Cellular and Molecular Neurobiology (CMN) Research Group at the IGTP have developed and established a novel, reproducible and minimally invasive stroke model in pigs through an endovascular approach. The work has been conducted at the Centre for Comparative Medicine and Bioimage (CMCiB), a centre devoted to translational medicine at the very core of the Can Ruti Campus in Badalona together with the IGTP and the Germans Trias i Pujol University Hospital.