Mesenchymal stem cells reveal mechanisms of action in regulatory B cells independent of interleukin-10 useful for their identification and monitoring

Researchers from the REMAR-IVECAT ("Kidney Related Diseases Research" and "Innovation in VEsicles and Cells for Application in Therapy") group, from the Germans Trias i Pujol Research Institute (IGTP), identify molecular pathways in regulatory B cells that are essential for their therapeutic applications. In the article that has been recently published in Frontiers in Immunology, the use of mesenchymal stem cells has allowed distinguishing the molecules that are essential to monitoring regulatory B cells in kidney transplants. 

Largest genetic study on stroke to date improves risk prediction

• A group of investigators from the Research Institute of the Hospital de la Santa Creu i Sant Pau - IIB Sant Pau has led the analysis of Spanish data from the largest international study carried out to date on the genetics of stroke risk.
• The results, published by the prestigious journal Nature, allow us to predict, with much more precision, the risk that a person may suffer a stroke. In addition, they provide valuable information on the biological processes involved in this disease, which is helping to find new, more effective treatments.
• The study analyzed data from the International Stroke Genetics Consortium, of which the Spanish Genestroke consortium is a member, and the GCAT|Genomes for Life cohort, from the Germans Trias i Pujol Research Institute (IGTP).