IGTP | Germans Trias i Pujol Research Institute

News

27/11/2025 - Campus Can Ruti, Research

New study maps the landscape of KRAS mutations and targeted therapies in colorectal cancer

A team of researchers from IGTP and ICO has studied alterations in the KRAS gene in colorectal cancer by combining genomic analyses with a systematic review of targeted compounds and clinical trials. Their findings, published in the journal npj Precision Oncology, provide and updated overview to guide future advances in this cancer's treatment.

21/11/2025 - Research

A new cellular model reveals which mutations drive progression to myelodysplastic syndrome and leukemia in patients with GATA2 deficiency

A research team has created the first humanised cellular model to study GATA2 deficiency, a rare genetic disorder that predisposes individuals to severe blood conditions such as myelodysplastic syndrome and leukaemia. The study shows that, although the initial GATA2 mutation weakens haematopoietic stem cells, it is additional mutations -particularly in the SETBP1 gene- that drive disease progression.

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Events

Thursday 27 November

A potential transition from a concentrated to a generalized HIV epidemic: the case of Madagascar

David Alonso Giménez
Llicenciat i Doctor en física; Departament d’Ecologia continental, al Grup de recerca d’Ecologia teòrica i computacional: CEAB (CSIC)

Wednesday 03 December