Publications
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Gutierrez-Chamorro, L, Felip, E, Castella, E, Quiroga, V, Ezeonwumelu, IJ, Angelats, L, Esteve, A, Perez-Roca, L, Martinez-Cardus, A, Fernandez, PL, Ferrando-Diez, A, Pous, A, Bergamino, M, Cirauqui, B, Romeo, M, Teruel, I, Mesia, R, Clotet, B, Riveira-Munoz, E, Margeli, M and Ballana, E.
SAMHD1 expression is a surrogate marker of immune infiltration and determines prognosis after neoadjuvant chemotherapy in early breast cancer
Cellular Oncology 47(1): 189-208
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Rubió-Casadevall, J, Cirauqui, BC, Trufero, JM, Serrahima, MP, Castaño, AG, Maseda, AC, Docampo, LI, Segura, PP, Lenza, IC, Calderón, VG, Salvà, JF, Alvarez, CP, Hernandez, I, Morillo, ED, Conde, MC, Galán, JM, Sánchez, MD, Quiroga, V, Ortega, E and Mesia, R.
TTCC-2019-02: real-world evidence of first-line cetuximab plus paclitaxel in recurrent or metastatic squamous cell carcinoma of the head and neck
Frontiers in Oncology 13:
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Marruecos-Querol, J, Rubio-Casadevall, J, Lozano, A, Buxo, M, Puigdemont, M, Linares, I, Planas, I, Vayreda, J, Cirauqui, B, Taberna, M, Quiroga, V, Tobed, M, Bores, A, Recalde, S, Saigi, M, Felip, E, Eraso, A and Mesia, R.
Validation of a prognostic model for predicting larynx preservation outcome (TALK score) in a Southern European population
CLINICAL & TRANSLATIONAL ONCOLOGY 25(8): 2384-2392
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Fontanals, S, Esteve, A, Gonzalez, A, Ibanez, C, Martinez, J, Mesia, R and Clopes, A.
Real-world treatment outcomes of medicines used in special situations (off-label and compassionate use) in oncology and hematology: A retrospective study from a comprehensive cancer institution
Cancer Medicine 12(16): 17112-17125
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Pérez, OM, Benavides, JM, Fernandez, TG, Prio, SG, Domínguez, RR, Nin, RM and Estela, AC.
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study
Expert Review of Clinical Pharmacology :
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Wildsmith, S, Li, WM, Wu, S, Stewart, R, Morsli, N, Raja, R, Zhang, Q, Ye, JB, He, PL, Shetty, J, Yovine, A, Holoweckyj, N, Real, K, Walker, J, Wrona, M, de los Reyes, M, Barker, C, Whiteley, J, Haddad, R, Licitra, L, Ferris, R, Fayette, J, Zandberg, DP, Siu, LL and Mesia, R.
Tumor Mutational Burden as a Predictor of Survival with Durvalumab and/or Tremelimumab Treatment in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Clinical Cancer Research 29(11): 2066-2074
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Cortellini, A, Tabernero, J, Mukherjee, U, Salazar, R, Sureda, A, Maluquer, C, Ferrante, D, Bower, M, Sharkey, R, Mirallas, O, Plaja, A, Cucurull, M, Mesia, R, Dalla Pria, A, Newsom-Davis, T, Van Hemelrijck, M, Sita-Lumsden, A, Apthorp, E, Vincenzi, B, Fazio, GRD, Tonini, G, Pantano, F, Bertuzzi, A, Rossi, S, Brunet, J, Lambertini, M, Pedrazzoli, P, Biello, F, D'Avanzo, F, Lee, AJX, Shawe-Taylor, M, Rogers, L, Murphy, C, Cooper, L, Andaleeb, R, Khalique, S, Bawany, S, Ahmed, S, Carmona-Garcia, MC, Fort-Culillas, R, Liñan, R, Zoratto, F, Rizzo, G, Perachino, M, Doonga, K, Gaidano, G, Bruna, R, Patriarca, A, Martinez-Vila, C, Criado, IP, Giusti, R, Mazzoni, F, Antonuzzo, L, Santoro, A, Parisi, A, Queirolo, P, Aujayeb, A, Rimassa, L, Diamantis, N, Bertulli, R, Fulgenzi, CAM, D'Alessio, A, Ruiz-Camps, I, Saoudi-Gonzalez, N, Illescas, DG, Medina, I, Fox, L, Gennari, A, Aguilar-Company, J and Pinato, DJ.
SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
LANCET ONCOLOGY 24(4): 335-346
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Fernandez, SE, Sun, C, Sole-Blanch, C, Boada, A, Martinez-Cardus, A and Manzano, JL.
Immunotherapy Resumption/Rechallenge in Melanoma Patients after Toxicity: Do We Have Another Chance?
Pharmaceutics 15(3):
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Gutierrez-Chamorro, L, Felip, E, Bernat-Peguera, A, Ezeonwumelu, IJ, Teruel, I, Martinez-Cardus, A, Clotet, B, Riveira-Munoz, E, Romeo, M, Margeli, M and Ballana, E.
SAMHD1 expression modulates innate immune activation and correlates with ovarian cancer prognosis
Frontiers in Immunology 14:
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Harrington, KJ, Burtness, B, Greil, R, Soulieres, D, Tahara, M, de Castro, G, Psyrri, A, Brana, I, Baste, N, Neupane, P, Bratland, A, Fuereder, T, Hughes, BGM, Mesia, R, Ngamphaiboon, N, Rordorf, T, Ishak, WZW, Lin, JX, Gumuscu, B, Swaby, RF and Rischin, D.
Pembrolizumab With or Without Chemotherapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Updated Results of the Phase III KEYNOTE-048 Study
JOURNAL OF CLINICAL ONCOLOGY 41(4): 790
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de Luna, CJ, Fernandez, E, Mesia, R and Clopes, A.
Clinical practice guidelines for the optimization of hemato-oncological care: the ICOPraxis
CLINICAL & TRANSLATIONAL ONCOLOGY 25(2): 555-559
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Hitt, R, Mesia, R, Lozano, A, Docampo, LI, Grau, JJ, Taberna, M, Rubio-Casadevall, J, Martinez-Trufero, J, Morillo, ED, Giron, CG, Estevez, SV, Cirauqui, B and Cruz-Hernandez, JJ.
Randomized phase 3 noninferiority trial of radiotherapy and cisplatin vs radiotherapy and cetuximab after docetaxel-cisplatin-fluorouracil induction chemotherapy in patients with locally advanced unresectable head and neck cancer
Oral Oncology 134:
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Prat, A, Paz-Ares, L, Juan, M, Felip, E, Garralda, E, Gonzalez, B, Arance, A, Martin-Liberal, J, Gavila, J, Lopez-Gonzalez, A, Cejalvo, JM, Izarzugaza, Y, Amillano, K, Corbacho, JG, Saura, C, Racca, F, Hierro, C, Sanfeliu, E, Gonzalez, X, Canes, J, Villacampa, G, Salvador, F, Pascual, T, Mesia, R, Cervantes, A and Tabernero, J.
SOLTI-1904 ACROPOLI TRIAL: efficacy of spartalizumab monotherapy across tumor-types expressing high levels of PD1 mRNA
Future Oncology 18(34): 3791-3800
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Trigo, J, Garcia-Cosio, M, Garcia-Castano, A, Goma, M, Mesia-Nin, R, Ruiz-Bravo, E, Soria-Rivas, A, Castillo, P, Brana-Garcia, I and Alberola-Ferranti, M.
Recommendations for the use of biomarkers for head and neck cancer, including salivary gland tumours: a consensus of the Spanish Society of Medical Oncology and the Spanish Society of Pathology
CLINICAL & TRANSLATIONAL ONCOLOGY 24(10): 1890-1902
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Saigi, M, Carcereny, E, Moran, T, Cucurull, M, Hernandez, A, Pros, E, Sanchez-Cespedes, M, Domenech, M and Martinez-Cardus, A.
Biological and clinical perspectives of the actionable gene fusions and amplifications involving tyrosine kinase receptors in lung cancer
Cancer Treatment Reviews 109:
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Marin-Jimenez, JA, Oliva, M, Martin, PP, Cabezas-Camarero, S, Serrahima, MP, Masedo, GV, Borbalas, AL, Martin, MNC, Esteve, A, Moreno, MCI, Altamis, EV, Hortiguela, LA, Sanz, MT, Perez-Segura, P and Mesia, R.
Paclitaxel Plus Cetuximab as Induction Chemotherapy for Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Unfit for Cisplatin-Based Chemotherapy
Frontiers in Oncology 12:
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Pinato, DJ, Aguilar-Company, J, Ferrante, D, Hanbury, G, Bower, M, Salazar, R, Mirallas, O, Sureda, A, Plaja, A, Cucurull, M, Mesia, R, Townsend, S, Jackson, A, Dalla Pria, A, Newsom-Davis, T, Handford, J, Sita-Lumsden, A, Apthorp, E, Vincenzi, B, Bertuzzi, A, Brunet, J, Lambertini, M, Maluquer, C, Pedrazzoli, P, Biello, F, Sinclair, A, Bawany, S, Khalique, S, Rossi, S, Rogers, L, Murphy, C, Belessiotis, K, Carmona-Garcia, MC, Sharkey, R, Garcia-Illescas, D, Rizzo, G, Perachino, M, Saoudi-Gonzalez, N, Doonga, K, Fox, L, Roldan, E, Gaidano, G, Ruiz-Camps, I, Bruna, R, Patriarca, A, Martinez-Vila, C, Cantini, L, Zambelli, A, Giusti, R, Mazzoni, F, Caliman, E, Santoro, A, Grosso, F, Parisi, A, Queirolo, P, Aujayeb, A, Rimassa, L, Prat, A, Tucci, M, Libertini, M, Grisanti, S, Mukherjee, U, Diamantis, N, Fusco, V, Generali, D, Provenzano, S, Gennari, A, Tabernero, J and Cortellini, A.
Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study
LANCET ONCOLOGY 23(7): 865-875
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Arribas, L, Sabate-Llobera, A, Domingo, MC, Taberna, M, Sospedra, M, Martin, L, Gonzalez-Tampan, AR, Pallares, N, Mesia, R and Baracos, VE.
Assessing dynamic change in muscle during treatment of patients with cancer: Precision testing standards
Clinical Nutrition 41(5): 1059-1065
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Bernat-Peguera, A, Trigueros, M, Ferrando-Diez, A, Ibanez, C, Bystrup, S, Martinez-Cardus, A, Margeli, M and Martinez-Balibrea, E.
Efficacy of CT-P6 (trastuzumab biosimilar) versus reference trastuzumab in combination with pertuzumab in HER2-positive early-stage breast cancer: Preclinical and real-life clinical data
Breast 62: 1-9
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Dominguez, AR, Cirauqui, B, Castano, AG, Cabellos, RA, Maseda, AC, Fernandez, BC, Rey, LI, Rubio-Casadevall, J, Arrazubi, V and Mesia, R.
SEOM-TTCC clinical guideline in nasopharynx cancer (2021)
CLINICAL & TRANSLATIONAL ONCOLOGY 24(4): 670-680
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Pardo, JC, Sanhueza, T, de Porras, VR, Etxaniz, O, Rodriguez, H, Martinez-Cardus, A, Grande, E, Castellano, D, Climent, MA, Lobato, T, Estudillo, L, Jorda, M, Carrato, C and Font, A.
Prognostic Impact of CD36 Immunohistochemical Expression in Patients with Muscle-Invasive Bladder Cancer Treated with Cystectomy and Adjuvant Chemotherapy
Journal of Clinical Medicine 11(3):
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Felip, E, Gutierrez-Chamorro, L, Gomez, M, Garcia-Vidal, E, Romeo, M, Moran, T, Layos, L, Perez-Roca, L, Riveira-Munoz, E, Clotet, B, Fernandez, PL, Mesia, R, Martinez-Cardus, A, Ballana, E and Margeli, M.
Modulation of DNA Damage Response by SAM and HD Domain Containing Deoxynucleoside Triphosphate Triphosphohydrolase (SAMHD1) Determines Prognosis and Treatment Efficacy in Different Solid Tumor Types
Cancers 14(3):
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Arrazubi, V, Cajaraville, G, Cantero, D, Giralt, J, Mesia, R, Monje, F, Rueda, A, Sistiaga, A, Suarez, J, Mut, A, Comellas, M and Lizan, L.
Defining a Standard Set of Health Outcomes for Patients With Squamous Cell Carcinoma of the Head and Neck in Spain
Frontiers in Oncology 11: 747520-747520
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Maurits, JSF, van der Zanden, LFM, Diekstra, MHM, Ambert, V, Castellano, D, Garcia-Donas, J, Troyas, RG, Guchelaar, HJ, Jaehde, U, Junker, K, Martinez-Cardus, A, Radu, MT, Rodriguez-Antona, C, Roessler, M, Warren, A, Eiseng, T, Oosterwijk, E, Kiemeneya, LALM and Vermeulen, SH.
Logical Imputation to Optimize Prognostic Risk Classification in Metastatic Renal Cell Cancer
Kidney Cancer 6(3): 169-178
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Bossi, P, Trama, A, Bernasconi, A, Grisanti, S, Mohamad, I, Galiana, IL, Ozyar, E, Franco, P, Vecchio, S, Bonomo, P, Cirauqui, BC, El-Sherify, M, Ursino, S, Argiris, A, Pan, J, Wittekindt, C, D'Angelo, E, Costa, L, Buglione, M, Johnson, J, Airoldi, M, Mesia, R, Resteghini, C, Licitra, L and Orlandi, E.
Nasopharyngeal cancer in non-endemic areas: Impact of treatment intensity within a large retrospective multicentre cohort
European Journal of Cancer 159: 194-204
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Arribas, L, Sabate-Llobera, A, Taberna, M, Pallares, N, Marin, AN, Virgili, N, Hurtos, L, Peiro, I, Vilajosana, E, Lozano, A, Baracos, V and Mesia, R.
Adequacy of nutritional support using computed tomography (CT) in patients with head and neck cancer (HNC) during chemo-radiotherapy (CRT)
European Journal of Clinical Nutrition 75(10): 1515-1519
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Lozano, A, Marruecos, J, Rubio, J, Farre, N, Gomez-Millan, J, Morera, R, Planas, I, Lanzuela, M, Vazquez-Masedo, MG, Cascallar, L, Giralt, J, Escames, G, Valenti, V, Grima, P, Bosser, R, Tarrago, C and Mesia, R.
Randomized placebo-controlled phase II trial of high-dose melatonin mucoadhesive oral gel for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing radiation therapy concurrent with systemic treatment
CLINICAL & TRANSLATIONAL ONCOLOGY 23(9): 1801-1810
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Domènech M, Muñoz Marmol AM, Mate JL, Estival A, Moran T, Cucurull M, Saigi M, Hernandez A, Sanz C, Hernandez-Gallego A, Urbizu A, Martinez-Cardus A, Bernat A and Carcereny E.
Correlation between PD-L1 expression and MET gene amplification in patients with advanced non-small cell lung cancer and no other actionable oncogenic driver.
Oncotarget 12(18): 1802-1810
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Arribas, L, Plana, M, Taberna, M, Sospedra, M, Vilarino, N, Oliva, M, Pallares, N, Tampan, ARG, Del Rio, LM, Mesia, R and Baracos, V.
Predictive Value of Skeletal Muscle Mass in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Patients Treated With Immune Checkpoint Inhibitors
Frontiers in Oncology 11:
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Pinato, DJ, Scotti, L, Gennari, A, Colomba-Blameble, E, Dolly, S, Loizidou, A, Chester, J, Mukherjee, U, Zambelli, A, Aguilar-Company, J, Bower, M, Galazi, M, Salazar, R, Bertuzzi, A, Brunet, J, Mesia, R, Sita-Lumsden, A, Colomba, J, Pommeret, F, Segui, E, Biello, F, Generali, D, Grisanti, S, Rizzo, G, Libertini, M, Moss, C, Evans, JS, Russell, B, Wuerstlein, R, Vincenzi, B, Bertulli, R, Ottaviani, D, Linan, R, Marrari, A, Carmona-Garcia, MC, Sng, CCT, Tondini, C, Mirallas, O, Tovazzi, V, Fotia, V, Cruz, CA, Saoudi-Gonzalez, N, Felip, E, Lloveras, AR, Lee, AJX, Newsom-Davis, T, Sharkey, R, Chung, C, Garcia-Illescas, D, Reyes, R, Wong, YNS, Ferrante, D, Marco-Hernandez, J, Ruiz-Camps, I, Gaidano, G, Patriarca, A, Sureda, A, Martinez-Vila, C, de Torre, AS, Rimassa, L, Chiudinelli, L, Franchi, M, Krengli, M, Santoro, A, Prat, A, Tabernero, J, Hemelrijck, MV, Diamantis, N and Cortellini, A.
Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study
European Journal of Cancer 150: 190-202
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Bernat-Peguera, A, Navarro-Ventura, J, Lorenzo-Sanz, L, da Silva-Diz, V, Bosio, M, Palomero, L, Penin, RM, Sidelnikova, DP, Bermejo, JO, Taberna, M, Vilarino, N, Piulats, JM, Mesia, R, Vinals, JM, Gonzalez-Suarez, E, Capella-Gutierrez, S, Villanueva, A, Vinals, F and Munoz, P.
FGFR Inhibition Overcomes Resistance to EGFR-targeted Therapy in Epithelial-like Cutaneous Carcinoma
Clinical Cancer Research 27(5): 1491-1504
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Esteve-Codina, A, Alameda, F, Carrato, C, Pineda, E, Arpi, O, Martinez-Garcia, M, Mallo, M, Gut, M, Dabad, M, Tortosa, A, Del Barco, S, Capellades, J, Puig, J, Gallego, O, Pujol, T, Oleaga, L, Gil-Gil, M, De Quintana-Schmidt, C, Valduvieco, I, Martinez-Cardus, A, Bellosillo, B, Munoz-Marmol, AM, Esteve, A, Domenech, M, Camins, A, Craven-Bartle, J, Villa, S, Marruecos, J, Domenech, S, de la Iglesia, N and Balana, C.
RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP-negative Glioblastoma
Clinical Cancer Research 27(2): 645-655
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Falco, A, de Oliveira, TB, Cacicedo, J, Ospina, AV, Ticona, MA, Galindo, H, Pereira, MD, Aguilar-Ponce, JL, Rueda-Dominguez, A, Soria, T, Taberna, M, Iglesias, L, Sowley, T and Mesia, R.
Ibero-American Expert Consensus on Squamous Cell Carcinoma of the Head and Neck Treatment in Patients Unable to Receive Cisplatin: Recommendations for Clinical Practice
Cancer Management and Research 13: 6689-6703
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Oliveira, TB, Mesia, R, Falco, A, Hsieh, JCH, Yokota, T, Saada-Bouzid, E, Schmitz, S, Elicin, O, Giacomelli, L and Bossi, P.
Defining the needs of patients with recurrent and/or metastatic head and neck cancer: An expert opinion
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 157:
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Mena, M, Frias-Gomez, J, Taberna, M, Quiros, B, Marquez, S, Clavero, O, Baena, A, Lloveras, B, Alejo, M, Leon, X, Garcia, J, Mesia, R, Bermejo, O, Bonfill, T, Aguila, A, Guix, M, Hijano, R, Pavon, MA, Torres, M, Tous, S, Cleries, R and Alemany, L.
Epidemiology of human papillomavirus-related oropharyngeal cancer in a classically low-burden region of southern Europe
Scientific Reports 10(1):
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Viros Porcuna D, Pollan Guisasola C, Viña Soria C, Cirauqui Cirauqui B, Pardo Muñoz L, Collurá F and Mesia Nin R.
Transoral robotic surgery for squamous cell carcinoma of the oropharynx in a primarily human papillomavirus-negative patient population.
CLINICAL & TRANSLATIONAL ONCOLOGY 22(8): 1303-1311
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Mattesen TB, Rasmussen MH, Sandoval J, Ongen H, Árnadóttir SS, Gladov J, Martinez-Cardus A, de Moura MC, Madsen AH, Laurberg S, Dermitzakis ET, Esteller M, Andersen CL and Bramsen JB.
Publisher Correction: MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer.
Nature Communications 11(1): 2880-2880
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Antelo G, Hierro C, Fernández JP, Baena E, Bugés C, Layos L, Manzano JL, Caro M and Mesia R.
Rectal neuroendocrine carcinoma: case report of a rare entity and perspective review of promising agents.
Drugs in Context 9:
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Mattesen, TB, Rasmussen, MH, Sandoval, J, Ongen, H, Arnadottir, SS, Gladov, J, Martinez-Cardus, A, Castro de Moura, M, Madsen, AH, Laurberg, S, Dermitzakis, ET, Esteller, M, Andersen, CL and Bramsen, JB.
MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
Nature Communications 11(1): 2025-2025
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Castellvi, M, Felip, E, Ezeonwumelu, IJ, Badia, R, Garcia-Vidal, E, Pujantell, M, Gutierrez-Chamorro, L, Teruel, I, Martinez-Cardus, A, Clotet, B, Riveira-Munoz, E, Margeli, M and Ballana, E.
Pharmacological Modulation of SAMHD1 Activity by CDK4/6 Inhibitors Improves Anticancer Therapy
Cancers 12(3):
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Capdevila, J, Arques, O, Mora, JRH, Matito, J, Caratu, G, Mancuso, FM, Landolfi, S, Barriuso, J, Jimenez-Fonseca, P, Lopez, CL, Garcia-Carbonero, R, Hernando, J, Matos, I, Paolo, N, Hernandez-Losa, J, Esteller, M, Martinez-Cardus, A, Tabernero, J, Vivancos, A and Palmer, HG.
Epigenetic EGFR Gene Repression Confers Sensitivity to Therapeutic BRAFV600E Blockade in Colon Neuroendocrine Carcinomas
Clinical Cancer Research 26(4): 902-909
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Mesia, R, Bossi, P, Hansen, AR, Hsieh, CY, Licitra, LF, Tan, EH, Chen, P, Miller, J, Siu, LL and Haddad, RI.
Phase II study of CC-486 (oral azacitidine) in previously treated patients with locally advanced or metastatic nasopharyngeal carcinoma
European Journal of Cancer 123: 138-145
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Castet, F, Brenes, J, Taberna, M and Mesia, R.
The emergence of long-term survivors in recurrent and metastatic squamous cell head and neck cancer
Current Opinion in Oncology 31(3): 160-168
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Marin, M, Gudiol, C, Castet, F, Oliva, M, Peiro, I, Royo-Cebrecos, C, Carratala, J and Mesia, R.
Bloodstream infection in patients with head and neck cancer: a major challenge in the cetuximab era
CLINICAL & TRANSLATIONAL ONCOLOGY 21(2): 187-196
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Oliva, M, Spreafico, A, Taberna, M, Alemany, L, Coburn, B, Mesia, R and Siu, LL.
Immune biomarkers of response to immune-checkpoint inhibitors in head and neck squamous cell carcinoma
Annals of Oncology 30(1): 57-67