At the IGTP TODAY
A new study provides a powerful way to study infections in environments that closely mimic human organs. The strategy, tested in a bone-marrow-on-chip model, was developed by researchers from ISGlobal, IGTP, I3S at Porto University, and IN2UB, as part of the HIDDENVIVAX project, funded by "la Caixa" Foundation.
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Provides a new perspective: what matters is not only which previous diseases a person has, but also the order in which they appeared and how they interact. This approach makes it possible to identify risk profiles for long COVID that had not been detected until now. The research was conducted within the framework of the COVICAT study, coordinated in collaboration with ISGlobal.
A project led by the Germans Trias i Pujol University Hospital and Research Institute has developed an AI-based facial recognition system, AcroFace, capable of detecting early signs of acromegaly with 93% accuracy. The researchers are now conducting a larger pilot study with 4,000 images from the general population to confirm these promising results and improve early diagnosis of this rare disease.
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Researchers from the IGTP and HUGTiP have reviewed the current knowledge on the use of tear-derived extracellular vesicles as a source of biomarkers for both ocular and neurodegenerative diseases. They highlight the advantages of this approach compared with more invasive methods and discuss the remaining challenges for its clinical application.
The demonstration of the vaccine's efficacy in its preclinical phase was carried out at the Comparative Medicine and Bioimage Centre of Catalonia, a trategic project of IGTP.
A clinical trial involving 40 patients, led by IrsiCaixa and IGTP and conducted at HUGTiP, confirms that the RUTI® vaccine, owned by Archivel Farma, enhances the effectiveness of the current treatment for non-muscle-invasive bladder cancer.
A study led by GCAT-IGTP links the VEGFA protein to long COVID, especially in postmenopausal women, suggesting a vascular mechanism behind persistent symptoms. The findings highlight the need to consider sex and hormonal status in long COVID research and treatment.
CEEISCAT and the Grupo de Trabajo sobre Tratamientos del VIH (gTt-VIH) announce the start of data collection for the SEXPROM Study, a pioneering investigation in Spain that will explore sexual satisfaction among people living with HIV, with a differentiated focus by gender and sexual orientation.
The combination of the drug nivolumab with chemotherapy improves survival in patients with high-risk head and neck cancer and could become the new standard treatment, according to the results of an international trial led by professionals from ICO, IGTP and IDIBELL.
A study coordinated from Badalona by IrsiCaixa, the Catalan Institute of Oncology and the Germans Trias i Pujol Research Institute (within the CARE programme) has identified KIMA, a genomic signature that makes it possible to anticipate which patients with HR+/HER2- breast cancer will respond less well to CDK4/6 inhibitors. The finding, published in the journal Clinical and Translational Medicine, may help personalize therapies and design new combinations.
