About
The Neurovascular Research Group has an experience of almost 20 years in multidisciplinary clinical-translational research in cerebral vascular pathology, with various cutting-edge clinical studies up to preclinical research at the molecular level and mechanisms of stroke.
This group was founded in 2006 by Dr Antoni Dávalos, and has been consolidated as a cerebrovascular diseases research group financed by Instituto de Salud Carlos III (ISCIII) from 2007 onwards. Since 2021, the team is led and coordinated by Dr Mònica Millán, current head of the Neurology Service of the Department of Neurosciences at Germans Trias i Pujol University Hospital (HUGTiP), with the support and clinical sub-coordination of Dr Natalia Pérez de la Ossa, head of section at HUGTiP’s Stroke Unit. The group is certified as a research team by AGAUR (2022) and is part of the RICORS-ictus network (2021).
The Stroke Unit at HUGTiP, accredited by the Spanish Society of Neurology (SEN) and by the European Stroke Organization (ESO), treats more than 1,000 stroke patients a year. It is one of the centres with the highest volume of reperfusion treatment in Catalonia, annually treating 120 patients with intravenous therapy and 150 patients with thrombectomy, with optimal intrahospital organisation and time metrics.
The general objectives of the Neurovascular Research Group are to carry out research of excellence, to develop and participate in clinical trials, to deepen the knowledge of the results achieved so far in basic and clinical research, to communicate to society and to the scientific community, and most importantly, to transfer their knowledge to clinical practice in the care of patients with cerebrovascular diseases. Thus, the group’s researchers aim for socially responsible research and innovation, prioritising research with the greatest potential to generate benefit for society, patients and their families.
Keywords: Stroke, thrombolysis, mechanical thrombectomy, endovascular treatment, intracranial hemorrhage, pre-hospital organization, neuroimaging, ischemia biomarkers, neuroprotection, post-stroke care, cognition.
Group leader
- Mònica Millán Torné, MD, PhD
Mònica Millán Torné, MD, PhD
Vascular neurologist, head of the Neuroscience Department, Germans Trias i Pujol University Hospital, Barcelona.
Dr Mònica Millán graduated in Medicine and Surgery from Universitat Autònoma de Barcelona in 1994. She joined as a Neurology resident at Germans Trias i Pujol University Hospital (HUGTIP), finishing the specialty in 2000. Since then, she has developed her career clinical professional, undergraduate and postgraduate teacher, researcher and management at HUGTiP, initially as an associate physician with special interest in cerebral vascular pathology, later as head of the Vascular Neurology Section and currently as head of the Neurology Department since 2018. In August 2023, she was appointed by the hospital management as clinical director of Neurosciences.
Dr Millán understands research as an inseparable binomial from the clinic, with the aim of improving the quality of life of patients with cerebral vascular diseases and that of their families. Among the developed lines of research, she has special interest in the role of iron in brain damage in patients with ischemic stroke (doctoral thesis), cerebral haemorrhage and in experimental studies stands out, as well as the neuroprotective role of iron chelators in cerebral ischemia (deferoxamine, apotransferrin) (Stroke 2007, Dis Markers 2008, Stroke 2010, Redox Biol 2018, Antioxidants 2022). Another line of research that Millán has developed is the demonstration of clinical benefit of mechanical thrombectomy (principal investigator of the REVASCAT study center, NEJM 2015), as well as the identification of clinical, radiological and procedural markers related to the clinical response of endovascular treatment in acute ischemic stroke.
She is co-author of more than 130 scientific articles (19 as main, corresponding or senior author), has participated in the writing of eight chapters or monographs, has obtained five competitive clinical research projects as principal investigator and has collaborated as co-investigator in five other academic projects. In addition, she has been the local-PI of 13 international clinical trials and co-investigator of 32 clinical trials both in the field of the acute phase and secondary prevention in ischemic or hemorrhagic stroke.
Her research activity is combined with undergraduate teaching activity as a professor at Universitat Autònoma de Barcelona and postgraduate (participation and organisation of specialised training courses), as well as with management responsibilities and care activity within the Neurology Department.
Contact: mmillan.germanstrias(ELIMINAR)@gencat.cat
ORCID: 0000-0002-4692-5936 - Natalia Pérez de la Ossa Herrero, MD, PhD
Natalia Pérez de la Ossa Herrero, MD, PhD
Vascular neurologist, coordinator of the Stroke Unit, Germans Trias i Pujol University Hospital, Barcelona.
Dr Pérez de la Ossa is a board-certified neurologist specialist in vascular neurology, with experience on acute treatment, intravenous and endovascular reperfusion therapies, neuroimaging and neurosonology. She graduated in Medicine and Surgery from Universitat Autònoma de Barcelona in 2000 and she joined as a neurology resident at Germans Trias i Pujol University Hospital (HUGTIP). Currently, she is the head of the Stroke Unit at HUGTIP, a comprehensive stroke center covering 1.5 million inhabitants. She is former director of the Catalan Stroke Program of the Health Department between 2020-2023. Her postgraduate medical training included a neurology residency and a neurovascular fellowship at HUGTIP, including a 6-month stay in the Royal Melboure Hospital, Australia.
Within her areas of interest, Dr Pérez de la Ossa has been working during the last years on the pre-hospital organisation of stroke care. She has collaborated on the publication of European guidelines (pre-hospital acute stroke care guideline and intravenous thrombolytic guideline). Since 2011, she leads a project based on the development, validation, training and implementation of a pre-hospital clinical scale (RACE scale) to rapidly identify stroke patients with high likelihood of large vessel occlusion in the pre-hospital setting, in order to deliver them to the angiographic suite with a minimum time delay. She was the co-chair of the RACECAT study performed in the entire region of Catalonia that aims to elucidate if direct transfer of stroke patients with a suspected LVO to an endovascular facility offers clinical benefit. Additionally, she has participated in multiple research trials, and has over 100 original articles and lectures in the field of cerebral vascular diseases.
Contact: nperez.germanstrias(ELIMINAR)@gencat.cat
ORCID: 0000-0002-6063-211X
Team
Alejandro Bustamante Rangel(ELIMINAR)
María Hernández Pérez(ELIMINAR)
Meritxell Gomis Cortina(ELIMINAR)
Laura Dorado Bouix(ELIMINAR)
Marina Martínez Sánchez(ELIMINAR)
Belén Flores-Pina(ELIMINAR)
Antoni Dávalos Errando(ELIMINAR)
Alicia Martínez Piñeiro(ELIMINAR)
Lucia Muñoz Narbona(ELIMINAR)
Martí Boix Coll(ELIMINAR)
Patricia Cuadras Collsamanta(ELIMINAR)
Paloma Puyalto De Pablo(ELIMINAR)
Cynthia María Cáceres Aguilar(ELIMINAR)
Carlos Hernán Castaño Duque(ELIMINAR)
Sebastià Remollo Friedemann(ELIMINAR)
Isabel Rodríguez Caamaño(ELIMINAR)
Carlos J. Domínguez Alonso(ELIMINAR)
Ana Rodríguez Hernández(ELIMINAR)
Alberto Blanco Ibañez(ELIMINAR)
Research lines
Therapies in patients with acute stroke
Neuroprotection
- Development of a neuroprotective agent (aptamer) in phase IIa-IIb clinical trial to demonstrate the safety and clinical benefit in patients with ischemic stroke candidates for endovascular treatment (APRIL Study).
- Co-leadership in the RACETOLL study to evaluate the safety of the same aptamer drug as a neuroprotectant administered in the ambulance in the pre-hospital phase.
- Development of a phase IIa/IIb clinical trial to evaluate the safety, dose determination and proof of concept of the benefit of apotransferrin in the treatment of ischemic stroke in patients treated with endovascular treatment.
Intravenous thrombolytic agents
- Participation and direction of multicentric studies that will demonstrate the therapeutic benefit of new intravenous thrombolytic agents such as tenecteplase (TNK-CAT study).
Endovascular treatment
- Demonstration of the safety of different technology and approaches for mechanical thrombectomy in acute stroke: AQUAS (Aperio Stent+ QTM Distal Aspiration Catheter), SEMTIC.
- Demonstration of the benefit of intra-arterial tPA post-complete recanalization in stroke patients treated with mechanical thrombectomy as a collaborating center of the CHOICE-2 study.
- Evaluation of the benefit of mechanical thrombectomy in new indications within international clinical trials such as in patients with extensive signs of incipient ischemia (LASTE, SELECT), mild symptoms (MOSTE) or distal occlusions (DISTAL trial).
- Development of electrophysiological device to identify patients with favorable response to mechanical thrombectomy (PROMISE20).
Intracranial haemorrhage
- Improvement of the prediction of mortality and functional prognosis to favor therapeutic decisions: Design and external validation of a novel and easier prognostic scale for mortality and functional recovery of patients with cerebral hemorrhage. To compare the prognostic performance of the new scale with published and more widely used prognostic scales.
- Leadership in the development of a study of minimally invasive surgery.
- Demonstration of the benefit of therapies with coagulation factors (recombinant FVII) as a collaborating center of the FASTEST trial study.
Territorial organisation for stroke care
Pre-hospital triage
- Development of new tools for pre-hospital triage to identify stroke sub-type (ischemic, hemorrhage and mimic-stroke) in the ambulance, as an evolution of the RACE scale, developed and validated by our group (RACE-PLUS project).
- Defintion of the most effective pre-hospital transfer circuits and algorithms depending on the patient's own characteristics, logistics, geography, etc... based on substudies of the RACECAT trial.
- Collaboration in international projects for the creation of artificial mathematical models through geomapping to define the optimal circuits in different geographical territories.
Multimodal neuroimaging techniques (CT and MR in acute stroke)
Patient selection for reperfusion treatment
- Determination of the best multimodal neuroimaging (CT or MRI) for the selection of stroke patients with criteria for mechanical thrombectomy.
- Determination of whether simple imaging techniques offer the same safety profile as advanced multimodal techniques in selecting patients for mechanical thrombectomy in an extended treatment window (VESTA trial).
- Establishment of new neuroimaging algorithms to improve patient selection.
Radiological biomarkers
- Study of mechanisms associated with cerebral infarction progression quantified with DWI lesion volume and radiological markers associated with clinical response and reperfusion damage (FURIAS trial).
Diagnostic and prognostic clinical and biological markers of stroke and its complications
Pneumonia associated with stroke (ELITE-SAP project)
- Validation of a panel of blood biomarkers for the prediction and diagnosis of stroke-associated pneumonia.
- Evaluation of pulmonary ultrasound for the prediction and diagnosis of pneumonia associated with stroke.
- Characterisation of the bronchoalveolar lavage fluid in animal models of stroke and its relationship with the development of pulmonary infections.
- Evaluation of new therapeutic targets and drugs for the prevention of pneumonia associated with stroke through the modulation of pulmonary immunity.
Cerebral thrombus analysis
- Validation of software for the radiological assessment of thrombus using artificial intelligence techniques that allow predicting the composition of the thrombus, the resistance to recanalization, with the aim of being able to establish the optimal treatment approach, as well as the etiology of the stroke and origin of the thrombus (ITACAT trial).
Neurocardiology
Neurological complications of invasive cardiac procedures
- Advanced neuropsychological and neuroimaging evaluation of the impact of cognitive impairment associated with different cardiac surgery techniques: aortic valve replacement through cardiac surgery vs transcatheter implantation (TAVI) (ARTICO study).
Identification of cardiac arrhythmias as a cause of stroke
- SRA (Stroke Risk Analysis) technology. Determination of the incidence of paroxysmal atrial fibrillation in patients with undetermined etiology of the stroke in the follow-up detected with the SRA system and with the insertable device.
- Identification of echocardiographic factors in combination with factors obtained in cardiac monitoring using the SRA system that allow predicting patients with atrial fibrillation.
Brain recovery and post-stroke care
- Implementation and evaluation of integrated multilevel care systems to pursue improvement in post-stroke care at discharge, early detection of complications and uncovered needs, and improvement in quality of life and health status.
- Incorporation of technological systems integrated into the IT systems that allow communication with the patient and family, management of expectations and collection of clinical results (PROMS and PREMS).
- Collaboration in a multicenter study to homogenize the care process and determine the clinical results focused on the value (HARMONICS).
Specific research lines
- Development of new tools for pre-hospital triage to identify stroke sub-type (RACE-PLUS project).
- Establishment of new neuroimaging algorithms to improve patient selection (VESTA study).
- Development of new technology and approaches for mechanical thrombectomy devices and monitoring in acute stroke.
- Study of mechanisms and radiological markers associated with cerebral infarction progression, clinical response and reperfusion damage (FURIAS study).
- Development of neuroprotective agents: aptamer and apotranferrin.
- Design and external validation of a novel prognostic scale for mortality and functional recovery of patients with cerebral haemorrhage.
- Development of a study of minimally invasive surgery in patients with cerebral haemorrhage.
- Diagnostic and prognostic clinical and biological markers of pneumonia associated with stroke (ELITE-SAP study)
- Impact of cognitive impairment associated with different cardiac surgery techniques: aortic valve replacement through cardiac surgery vs transcatheter implantation (TAVI) (ARTICO study).
- Implement and evaluate integrated multilevel care systems and incorporation of technological systems to pursue improvement in post-stroke care, early detection of complications and uncovered needs, and improvement in quality of life and health status (CAMÍ project).
Active projects
Grup de Recerca Neurovascular Germans Trias i Pujol (GRNV-GT)
PI: Mònica Millán Torné
Funding agency: Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR)
Agency code: 2021 SGR 00925
Duration: 2022 - 2025
RICORS-ICTUS
PI: Mònica Millán Torné
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: RD21/0006/0024
Duration: 2022 - 2024
Project RACE / RACE-PLUS
PI: Natalia Pérez de la Ossa
Funding agency: Fundació "La Caixa" / Llegat GT / Fundació Ictus
Duration: 2023 – 2025
Clinical trial to evaluate the administration of ApTOLL in ambulances and the neuroprotective effect in stroke patients. RACETOLL
PI: Natalia Pérez de la Ossa
Funding agency: Ministerio de Ciencia e Innovación
Agency code: CPP2021-008378
Duration: 2022 - 2024
Geospatial modeling for stroke care
PI: Natalia Pérez de la Ossa
Funding agency: NIH-National Institute of Neurological Disorders and Stroke
Agency code: 1R01NS127114-01
Duration: 2022 - 2027
Tratamiento del ictus en Ventana Extendida: optimización de la Selección radiológica y el modelo de TrAslado en los pacientes con un ictus de 6-24h (estudio VESTA)
PI: María Hernández Pérez
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI21/01548
Duration: 2022 - 2024
Evaluación del daño pulmonar como diana terapéutica contra la neumonía asociada al ictus (ELITE-SAP)
PI: Alejandro Bustamante Rangel
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI21/00939
Duration: 2022 - 2024
Blood-brain barrier dysfunction an oxidative stress modulation in brain arteriovenous malformations: a translational study of secondary injury after surgical resection
PI: Laura Dorado Bouix
Funding agency: Fundació La Marató TV3
Agency code: 202035.32
Duration: 2021 - 2024
Cirugía precoz y mínimamente invasiva en hematomas intracraneales: estudio translacional multicéntrico del papel de los biomarcadores iniciales en el daño cerebral secundario subagudo
PI: Ana Rodríguez
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI22/01290
Duration: 2023 – 2025
Past projects
Fecal incontinence after acute stroke (FINISH Study): understanding pathophysiological mechanisms and new frontiers in its treatment
PI: Mònica Millán Torné
Funding agency: Fundació La Marató TV3
Agency code: 201718.10
Duration: 2018 - 2022
NeuroToll - Desarrollo y validación clínica de un aptámero terapéutico para tratamiento del ictus isquémico agudo
PI: Antoni Dávalos Errando
Funding agency: Ministerio de Ciencia, Innovación y Universidades
Agency code: RTC-2017-6651-1
Duration: 2018 - 2022
ITACAT: Impact of Thrombus Analysis in stroke patients in CATalonia
PI: Laura Dorado Bouix
Funding agency: Fundació La Marató TV3
Agency code: 201719.31
Duration: 2018 - 2022
BraiN20, the new standard of care to improve the management of Acute Ischemic Stroke (AIS) patients
PI: Alicia Martínez Piñeiro
Funding agency: Fundació "La Caixa"
Agency code: CC21-10016
Duration: 2021 - 2023
Evaluación Neuropsicológica y por Neuroimagen Avanzada del impacto del Deterioro Cognitivo en la Sustitución Valvular Aórtica Convencional comparada con el Implante Transcatéter
PI: Meritxell Gomis Cortina
Funding agency: Instituto de Salud Carlos III (ISCIII)
Agency code: PI19/01397
Duration: 2020 - 2023
Scientific publications
Highlighted publications
Krishnamoorthy S, Singh G, Jose K J, Soman B, Foerch C, Kimberly WT, Millán M, Świtońska M, Maestrini I, Bordet R, Malhotra K, Mechtouff L, Sylaja PN. Biomarkers in the Prediction of Hemorrhagic Transformation in Acute Stroke: A Systematic Review and Meta-Analysis. Cerebrovasc Dis. 2022;51(2):235-247. DOI: 10.1159/000518570.
Renú A, Millán M, San Román L, Blasco J, Martí-Fàbregas J, Terceño M, Amaro S, Serena J, Urra X, Laredo C, Barranco R, Camps-Renom P, Zarco F, Oleaga L, Cardona P, Castaño C, Macho J, Cuadrado-Godía E, Vivas E, López-Rueda A, Guimaraens L, Ramos-Pachón A, Roquer J, Muchada M, Tomasello A, Dávalos A, Torres F, Chamorro Á; CHOICE Investigators. Effect of Intra-arterial Alteplase vs Placebo Following Successful Thrombectomy on Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke: The CHOICE Randomized Clinical Trial. JAMA. 2022 Mar 1;327(9):826-835. DOI: 10.1001/jama.2022.1645.
Millán M, Ramos-Pachón A, Dorado L, Bustamante A, Hernández-Pérez M, Rodríguez-Esparragoza L, Gomis M, Remollo S, Castaño C, Werner M, Wenger D, Rubio S, Domínguez-Lizarbe M, Terceño M, Paipa AJ, Rodríguez-Vázquez A, Boned S, Camps-Renom P, Cánovas D, Giralt E, López-Cancio E, Dávalos A, Ros-Roig J, Pérez de la Ossa N; Cat-SCR Consortium. Predictors of Functional Outcome After Thrombectomy in Patients With Prestroke Disability in Clinical Practice. Stroke. 2022 Mar;53(3):845-854. DOI: 10.1161/STROKEAHA.121.034960.
Martín-Aguilar L, Paré-Curell M, Dorado L, Pérez de la Ossa-Herrero N, Ramos-Pachón A, López-Cancio E, Fernández-Nofrerias E, Rodríguez-Leor O, Castaño C, Remollo S, Puyalto P, Cuadras P, Millán M, Dávalos A, Hernández-Pérez M. Ischaemic stroke as a complication of cardiac catheterisation. Clinical and radiological characteristics, progression, and therapeutic implications. Neurologia (Engl Ed). 2022 Apr;37(3):184-191. DOI: 10.1016/j.nrleng.2018.12.020.
Pérez de la Ossa N, Abilleira S, Jovin TG, García-Tornel Á, Jimenez X, Urra X, Cardona P, Cocho D, Purroy F, Serena J, San Román Manzanera L, Vivanco-Hidalgo RM, Salvat-Plana M, Chamorro A, Gallofré M, Molina CA, Cobo E, Davalos A, Ribo M; RACECAT Trial Investigators. Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial. JAMA. 2022 May 10;327(18):1782-1794. DOI: 10.1001/jama.2022.4404. Erratum in: JAMA. 2023 Apr 4;329(13):1123.
Cárcel-Márquez J, Muiño E, Gallego-Fabrega C, Cullell N, Lledós M, Llucià-Carol L, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, Álvarez-Sabín J, Molina CA, Ribó M, Jiménez-Conde J, Roquer J, Muñoz-Narbona L, Lopez-Cancio E, Millán M, Diaz-Navarro R, Vives-Bauza C, Serrano-Heras G, Segura T, Ibañez L, Heitsch L, Delgado P, Dhar R, Krupinski J, Delgado-Mederos R, Prats-Sánchez L, Camps-Renom P, Blay N, Sumoy L, de Cid R, Montaner J, Cruchaga C, Lee JM, Martí-Fàbregas J, Férnandez-Cadenas I. A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype. Front Cardiovasc Med. 2022 Jul 8;9:940696. DOI: 10.3389/fcvm.2022.940696.
García-Tornel Á, Seró L, Urra X, Cardona P, Zaragoza J, Krupinski J, Gómez-Choco M, Sala NM, Catena E, Palomeras E, Serena J, Hernandez-Perez M, Boned S, Olivé-Gadea M, Requena M, Muchada M, Tomasello A, Molina CA, Salvat-Plana M, Escudero M, Jimenez X, Davalos A, Jovin TG, Purroy F, Abilleira S, Ribo M, de la Ossa NP; RACECAT trial investigators. Workflow Times and Outcomes in Patients Triaged for a Suspected Severe Stroke. Ann Neurol. 2022 Dec;92(6):931-942. DOI: 10.1002/ana.26489.
Ramos-Pachón A, Rodríguez-Luna D, Martí-Fàbregas J, Millán M, Bustamante A, Martínez-Sánchez M, Serena J, Terceño M, Vera-Cáceres C, Camps-Renom P, Prats-Sánchez L, Rodríguez-Villatoro N, Cardona-Portela P, Urra X, Solà S, Del Mar Escudero M, Salvat-Plana M, Ribó M, Abilleira S, Pérez de la Ossa N, Silva Y; RACECAT Trial Investigators. Effect of Bypassing the Closest Stroke Center in Patients with Intracerebral Hemorrhage: A Secondary Analysis of the RACECAT Randomized Clinical Trial. JAMA Neurol. 2023 Oct 1;80(10):1028-1036. DOI: 10.1001/jamaneurol.2023.2754.
Hernández-Pérez M, Werner M, Remollo S, Martín C, Cortés J, Valls A, Ramos A, Dorado L, Serena J, Munuera J, Puig J, Pérez de la Ossa N, Gomis M, Carbonell J, Castaño C, Muñoz-Narbona L, Palomeras E, Domenech S, Massuet A, Terceño M, Davalos A, Millán M. Early and Delayed Infarct Growth in Patients Undergoing Mechanical Thrombectomy: A Prospective, Serial MRI Study. Stroke. 2023; 54: 217-225. DOI: 10.1161/STROKEAHA.122.039090.
Silva Y, Sánchez-Cirera L, Terceño M, Dorado L, Valls A, Martínez M, Abilleira S, Rubiera M, Quesada H, Llull L, Rodríguez-Campello A, Martí-Fàbregas J, Seró L, Purroy F, Payo I, García S, Cánovas D, Krupinski J, Mas N, Palomeras E, Cocho D, Font MÀ, Catena E, Puiggròs E, Pedroza C, Marín G, Carrión D, Costa X, Almendros MC, Torres I, Colom C, Velasquez JA, Diaz G, Jiménez X, Subirats T, Deulofeu A, Hidalgo V, Salvat-Plana M, Pérez de la Ossa N. Sex and gender differences in acute stroke care: metrics, access to treatment and outcome. Eur Stroke J. 2023 Jun;8(2):557-565. DOI: 10.1177/23969873231156260.
Additional information
Doctoral theses
Title: Determinació de variables pronòstiques de mortalitat i recuperació funcional en hemorràgia intracerebral
Author: Anna Ramos
Supervisors: Mònica Millàn, Maite Missis
University: Universitat Autònoma de Barcelona (UAB)
Date of defense: 27/10/2023
Title: Evaluación Neuropsicológica y por Neuroimagen avanzada del impacto del deterioro cognitivo en la sustitución valvular aórtica convencional comparada con el implante transcatéter (ARTiCO)
Author: Claudio Fernández
Supervisor: Meritxell Gomis
University: Universitat Autònoma de Barcelona (UAB)
Currently under preparation
Title: Evaluación del daño pulmonar como diana terapéutica en la neumonía asociada al ictus
Author: Diego Sahuquillo Barros
Supervisor: Alejandro Bustamante
University: Universitat Autònoma de Barcelona (UAB)
Currently under preparation
Title: Marcadores radiológicos evolutivos en el ictus agudo por oclusión de gran vaso: fenómeno de no reflow y rotura de barrera hematoencefálica
Author: Adrián Valls Carbó
Supervisor: María Hernández-Pérez
University: Universitat Autònoma de Barcelona (UAB)
Currently under preparation
Title: Caracterización del realce post-contraste como marcador de actividad inflamatoria de las placas de aterosclerosis intracraneal. Estudio Clínico-Básico
Author: Beatriz Gómez Vicente
Supervisor: Maria Hernández-Pérez
University: Universidad de Valladolid
Date of defense: 12/05/2023
Title: Predicción y diagnóstico de la neumonía asociada al ictus mediante biomarcadores ecográficos y sanguíneos
Author: Marina Martínez
Supervisors: Alejandro Bustamante, Natalia Pérez de la Ossa
University: Universitat Autònoma de Barcelona (UAB)
Currently under preparation
Title: Factores relacionados con la aparición de fibrilación auricular, insuficiencia cardíaca, y su pronóstico en Cataluña
Author: Felipe González Loyola
Supervisor: Alejandro Bustamante
University: Universitat Autònoma de Barcelona (UAB)
Currently under preparation
Time is Brain
Time is Brain is spin-off from IGTP created in 2020. The team developed BraiN20, a medical device which hopes to be the new standard of care to improve the management of Acute Ischemic Stroke (AIS) patients. PIs: Alicia Martínez-Piñeiro and Antoni Dávalos.
Others
- Group members participate in other research activities as members of various scientific committees or clinical trial safety committees, are part of scientific societies and collaborate as editors of international journals (Frontiers in Neurology, SVIN, others).
- Some of the team members participate in advisory activities to biomedical and pharmaceutical companies in the development of diagnostic devices and therapeutic strategies, such as the company Methinks, ApataTargets. They also actively participates in training activities, presentations, and advisory activities for different initiatives as the Angels Initiative which acts at a global level in the establishment of health systems and training professionals for the improvement of care stroke.
News
La aplicación de un protocolo de codificación del ictus retinal mejora la recuperación visual de los pacientes que reciben terapias de reperfusión
El 'Código Ictus Retina' actúa contra un tipo de ictus que puede provocar una pérdida de visión irreversible si no se actúa en 6 horas. Es único en Cataluña y en cinco años ha demostrado ser clave para recuperar la agudeza visual y evitar peores complicaciones en los pacientes del Hospital Germans Trias.
Cuatro proyectos del IGTP financiados con 1,7 millones de euros por el Ministerio de Ciencia e Innovación
El Instituto de Investigación Germans Trias i Pujol (IGTP) ha obtenido financiación para desarrollar cuatro proyectos presentados a la convocatoria competitiva "Proyectos de colaboración público-privada" de la Agencia Estatal de Investigación del Ministerio de Ciencia e Innovación, con un valor total de 1.706.019,92€.
Contact
Mònica Millán
(+34) 93 497 89 11
Natalia Pérez de la Ossa
More links
Mònica Millán Torné - HUGTiP webpage · Natalia Pérez de la Ossa - HUGTiP webpage · Donate via Amics de Can Ruti · Follow @NeuroHGTiP on X