Research
Enfermedades Infecciosas

Grupo de Investigación en Plasmodium vivax y Exosomas (PvREX)

Publications

  • Esteves, S, Lima, C, Costa, I, Osorio, H, Fernandez-Becerra, C, Santarem, N and Cordeiro-da-Silva, A.

    Characterization and Proteomic Analysis of Plasma EVs Recovered from Healthy and Diseased Dogs with Canine Leishmaniosis

    International Journal of Molecular Sciences 24(6):

    [doi:10.3390/ijms24065490]

  • Gualdron-Lopez, M, Diaz-Varela, M, Zanghi, G, Aparici-Herraiz, I, Steel, RWJ, Schafer, C, Cusco, P, Chuenchob, V, Kangwangransan, N, Billman, ZP, Olsen, TM, Gonzalez, JR, Roobsoong, W, Sattabongkot, J, Murphy, SC, Mikolajczak, SA, Borras, E, Sabido, E, Fernandez-Becerra, C, Flannery, EL, Kappe, SHI and del Portillo, HA.

    Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections br

    MOLECULAR & CELLULAR PROTEOMICS 21(10):

    [doi:10.1016/j.mcpro.2022.100406]

  • Herraiz, IA, Caires, HR, Castillo-Fernandez, O, Sima, N, Mendez-Mora, L, Risueno, RM, Sattabongkot, J, Roobsoong, W, Hernandez-Machado, A, Fernandez-Becerra, C, Barrias, CC and del Portillo, HA.

    Advancing Key Gaps in the Knowledge of Plasmodium vivax Cryptic Infections Using Humanized Mouse Models and Organs-on-Chips

    Frontiers in cellular and infection microbiology 12:

    [doi:10.3389/fcimb.2022.920204]

  • Madeira, RP, Meneghetti, P, de Barros, LA, Buck, PD, Mady, C, Ianni, BM, Fernandez-Becerra, C and Torrecilhas, AC.

    Isolation and molecular characterization of circulating extracellular vesicles from blood of chronic Chagas disease patients

    Cell Biology International 46(6): 883-894

    [doi:10.1002/cbin.11787]

  • Brito, MAM, Baro, B, Raiol, TC, Ayllon-Hermida, A, Safe, IP, Deroost, K, Figueiredo, EFG, Costa, AG, Armengol, MD, Sumoy, L, Almeida, ACG, Hounkpe, BW, De Paula, EV, Fernandez-Becerra, C, Monteiro, WM, del Portillo, HA and Lacerda, MVG.

    Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections

    Journal of Infectious Diseases 225(7): 1274-1283

    [doi:10.1093/infdis/jiaa177]

  • Fernandez-Becerra, C, Aparici-Herraiz, I and del Portillo, HA.

    Cryptic erythrocytic infections in Plasmodium vivax, another challenge to its elimination

    Parasitology International 87: 102527-102527

    [doi:10.1016/j.parint.2021.102527]

  • Aparici-Herraiz, I, Gualdron-Lopez, M, Castro-Cavadia, CJ, Carmona-Fonseca, J, Yasnot, MF, Fernandez-Becerra, C and del Portillo, HA.

    Antigen Discovery in Circulating Extracellular Vesicles From Plasmodium vivax Patients

    Frontiers in cellular and infection microbiology 11: 811390-811390

    [doi:10.3389/fcimb.2021.811390]

  • Elizalde-Torrent, A, Trejo-Soto, C, Mendez-Mora, L, Nicolau, M, Ezama, O, Gualdron-Lopez, M, Fernandez-Becerra, C, Alarcon, T, Hernandez-Machado, A and del Portillo, HA.

    Pitting of malaria parasites in microfluidic devices mimicking spleen interendothelial slits

    Scientific Reports 11(1): 22099-22099

    [doi:10.1038/s41598-021-01568-w]

  • Monteiro, EF, Fernandez-Becerra, C, Curado, I, Wunderlich, G, Hiyane, MI and Kirchgatter, K.

    Antibody Profile Comparison against MSP1 Antigens of Multiple Plasmodium Species in Human Serum Samples from Two Different Brazilian Populations Using a Multiplex Serological Assay

    Pathogens 10(9):

    [doi:10.3390/pathogens10091138]

  • Ketema, T, Bacha, K, Getahun, K, del Portillo, HA and Bassat, Q.

    Plasmodium vivax epidemiology in Ethiopia 2000-2020: A systematic review and meta-analysis

    PLoS Neglected Tropical Diseases 15(9):

    [doi:10.1371/journal.pntd.0009781]

  • Montaner-Tarbes, S, Fraile, L, Montoya, M and Del Portillo, H.

    Exosome-Based Vaccines: Pros and Cons in the World of Animal Health

    VIRUSES-BASEL 13(8):

    [doi:10.3390/v13081499]

  • Kho, S, Qotrunnada, L, Leonardo, L, Andries, B, Wardani, PAI, Fricot, A, Henry, B, Hardy, D, Margyaningsih, NI, Apriyanti, D, Puspitasari, AM, Prayoga, P, Trianty, L, Kenangalem, E, Chretien, F, Brousse, V, Safeukui, I, del Portillo, HA, Fernandez-Becerra, C, Meibalan, E, Marti, M, Price, RN, Woodberry, T, Ndour, PA, Russell, BM, Yeo, TW, Minigo, G, Noviyanti, R, Poespoprodjo, JR, Siregar, NC, Buffet, PA and Anstey, NM.

    Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study

    PLoS Medicine 18(5):

    [doi:10.1371/journal.pmed.1003632]

  • Gualdron-Lopez, M, Diaz-Varela, M, Toda, H, Aparici-Herraiz, I, Pedro-Cos, L, Lauzurica, R, Lacerda, MVG, Fernandez-Sanmartin, MA, Fernandez-Becerra, C and del Portillo, HA.

    Multiparameter Flow Cytometry Analysis of the Human Spleen Applied to Studies of Plasma-Derived EVs From Plasmodium vivax Patients

    Frontiers in cellular and infection microbiology 11: 596104-596104

    [doi:10.3389/fcimb.2021.596104]

  • Royo, F, Azkargorta, M, Lavin, JL, Clos-Garcia, M, Cortazar, AR, Gonzalez-Lopez, M, Barcena, L, del Portillo, HA, Yanez-Mo, M, Marcilla, A, Borras, FE, Peinado, H, Guerrero, I, Vales-Gomez, M, Cereijo, U, Sardon, T, Aransay, AM, Elortza, F and Falcon-Perez, JM.

    Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules

    Frontiers in Cell and Developmental Biology 8: 613583-613583

    [doi:10.3389/fcell.2020.613583]

  • Monteiro, W, Brito-Sousa, JD, Elizalde-Torrent, A, Botto-Menezes, C, Melo, GC, Fernandez-Becerra, C, Lacerda, M and del Portillo, HA.

    Cryptic Plasmodium chronic infections: was Maurizio Ascoli right?

    Malaria Journal 19(1): 440-440

    [doi:10.1186/s12936-020-03516-x]

  • Borgheti-Cardoso, LN, Kooijmans, SAA, Chamorro, LG, Biosca, A, Lantero, E, Ramirez, M, Avalos-Padilla, Y, Crespo, I, Fernandez, I, Fernandez-Becerra, C, del Portillo, HA and Fernandez-Busquets, X.

    Extracellular vesicles derived from Plasmodium-infected and non-infected red blood cells as targeted drug delivery vehicles

    International Journal of Pharmaceutics 587: 119627-119627

    [doi:10.1016/j.ijpharm.2020.119627]

  • Cortes-Serra, N, Mendes, MT, Mazagatos, C, Segui-Barber, J, Ellis, CC, Ballart, C, Garcia-Alvarez, A, Gallego, M, Gascon, J, Almeida, IC, Pinazo, MJ and Fernandez-Becerra, C.

    Plasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Disease

    Emerging Infectious Diseases 26(8): 1846-1851

    [doi:10.3201/eid2608.191042]

  • Monteiro, EF, Fernandez-Becerra, C, Araujo, MD, Messias, MR, Ozaki, LS, Duarte, AMRD, Bueno, MG, Catao-Dias, JL, Chagas, CRF, Mathias, BD, dos Santos, MG, Santos, SV, Holcman, MM, de Souza, JC and Kirchgatter, K.

    Naturally Acquired Humoral Immunity against Malaria Parasites in Non-Human Primates from the Brazilian Amazon, Cerrado and Atlantic Forest

    Pathogens 9(7):

    [doi:10.3390/pathogens9070525]

  • Cortes-Serra, N, Losada-Galvan, I, Pinazo, MJ, Fernandez-Becerra, C, Gascon, J and Alonso-Padilla, J.

    State-of-the-art in host-derived biomarkers of Chagas disease prognosis and early evaluation of anti-Trypanosoma cruzi treatment response

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1866(7):

    [doi:10.1016/j.bbadis.2020.165758]

  • Toda, H, Diaz-Varela, M, Segui-Barber, J, Roobsoong, W, Baro, B, Garcia-Silva, S, Galiano, A, Gualdron-Lopez, M, Almeida, ACG, Brito, MAM, de Melo, GC, Aparici-Herraiz, I, Castro-Cavadia, C, Monteiro, WM, Borras, E, Sabido, E, Almeida, IC, Chojnacki, J, Martinez-Picado, J, Calvo, M, Armengol, P, Carmona-Fonseca, J, Yasnot, MF, Lauzurica, R, Marcilla, A, Peinado, H, Galinski, MR, Lacerda, MVG, Sattabongkot, J, Fernandez-Becerra, C and del Portillo, HA.

    Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

    Nature Communications 11(1): 2761-2761

    [doi:10.1038/s41467-020-16337-y]

  • Llora-Batlle, O, Michel-Todo, L, Witmer, K, Toda, H, Fernandez-Becerra, C, Baum, J and Cortes, A.

    Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparum

    Science Advances 6(24):

    [doi:10.1126/sciadv.aaz5057]

  • Tubita, V, Segui-Barber, J, Lozano, JJ, Banon-Maneus, E, Rovira, J, Cucchiari, D, Moya-Rull, D, Oppenheimer, F, Del Portillo, H, Campistol, JM, Diekmann, F, Ramirez-Bajo, MJ and Revuelta, I.

    Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche

    Scientific Reports 9(1): 11177-11177

    [doi:10.1038/s41598-019-47581-y]

  • Montaner-Tarbes, S, del Portillo, HA, Montoya, M and Fraile, L.

    Key Gaps in the Knowledge of the Porcine Respiratory Reproductive Syndrome Virus (PRRSV)

    Frontiers in Veterinary Science 6: 38-38

    [doi:10.3389/fvets.2019.00038]